Baseline (t0)
|
30
|
57.22
|
29.0
|
30
|
58.06
|
29.1
|
After 3 month (t2)
|
25
|
49.0
|
24.92
|
22
|
56.44
|
30.53
|
After 6 month (t3)
|
18
|
35.65
|
25.37
|
18
|
64.91
|
31.25
|
Treatment effect (t0-t2) after 3 month p = 0.637, (t0-t3) after 6 month p = 0.013
|
Effect size (t0-t2) after 3 month -0.04, (t0-t3) after 6 month -0.71
|
Emotional fatigue
|
Intervention group (Arm A)
|
Control group (Arm B)
|
|
n
|
Mean
|
SD
|
n
|
Mean
|
SD
|
Baseline (t0)
|
30
|
46.67
|
32.5
|
30
|
44.44
|
30.27
|
After 3 month (t2)
|
25
|
33.67
|
25.63
|
22
|
43.18
|
34.85
|
After 6 month (t3)
|
18
|
27.31
|
27.54
|
18
|
46.05
|
33.26
|
Treatment effect (t0-t2) after 3 month p = 0.796, (t0-t3) after 6 month p = 0.156
|
Effect size (t0-t2) after 3 month -0.14, (t0-t3) after 6 month -0.35
|
Cognitive fatigue
|
Intervention group (Arm A)
|
Control group (Arm B)
|
|
n
|
Mean
|
SD
|
n
|
Mean
|
SD
|
Baseline (t0)
|
30
|
21.11
|
21.71
|
30
|
17.78
|
22.15
|
After 3 month (t2)
|
25
|
16.89
|
23.16
|
22
|
22.22
|
25.89
|
After 6 month (t3)
|
18
|
19.14
|
20.45
|
18
|
19.30
|
21.23
|
Treatment effect (t0-t2) after 3 month p = 0.248, (t0-t3) after 6 month p = 0.433
|
Effect size (t0-t2) after 3 month -0.24, (t0-t3) after 6 month -0.19
|
Interference with daily life
|
Intervention group (Arm A)
|
Control group (Arm B)
|
|
n
|
Mean
|
SD
|
n
|
Mean
|
SD
|
Baseline (t0)
|
30
|
2.53
|
0.94
|
30
|
2.30
|
1.09
|
After 3 month (t2)
|
25
|
2.20
|
1.04
|
22
|
2.64
|
1.00
|
After 6 month (t3)
|
18
|
1.89
|
0.96
|
18
|
3.05
|
0.97
|
Treatment effect (t0-t2) after 3 month p = 0.093, (t0-t3) after 6 month p = 0.006
|
Effect size (t0-t2) after 3 month -0.48, (t0-t3) after 6 month -0.91
|
Social sequelae
|
Intervention group (Arm A)
|
Control group (Arm B)
|
|
n
|
Mean
|
SD
|
n
|
Mean
|
SD
|
Baseline (t0)
|
30
|
1150
|
0.78
|
30
|
1.43
|
0.86
|
After 3 month (t2)
|
25
|
1.24
|
0.52
|
22
|
1.64
|
1.00
|
After 6 month (t3)
|
18
|
1.22
|
0.43
|
18
|
1.79
|
1.23
|
Treatment effect (t0-t2) after 3 month p = 0.129, (t0-t3) after 6 month p = 0.363
|
Effect size (t0-t2) after 3 month -0.40, (t0-t3) after 6 month -0.37 |