Skip to main content
. 2014 Jul 22;4:20. doi: 10.1186/s12348-014-0020-1

Table 1.

Major HLA genotypes associated with VKH disease

HLA genotype association Major findings Race References
HLA-DQA1*0301
100% of 57 VKH patients vs. 67.2% of 122 control subjects
Japanese
Islam et al. [[24]]
HLA-DQB1*0604
0% of 57 VKH patients vs. 15.6% of 122 control subjects, i.e., may be protective against VKH disease
Japanese
Islam et al. [[24]]
HLA-DRB1*0404
25% of 76 VKH patients vs. 9.8% of 256 healthy individuals
Mexican Mestizo
Alaez et al. [[40]]
HLA-DRB1*0405 95% of 40 VKH patients vs. 58.2% of DR4-positive healthy controls
Japanese
Shindo et al. [[28]]
54.1% of 37 VKH patients have HLA-DRB1*0405 with a relative risk of 11.76 over the general population
Highly admixed Brazilian
Goldberg et al. [[34]]
82.3% of 18 VKH patients vs. 9.3% of 128 control subjects
Korean
Kim et al. [[35]]
36.6% of 30 VKH patients vs. 6.9% of 29 control subjects
Saudi Arabian
Iqniebi et al. [[36]]
13.2% of 76 VKH patients vs. 0.4% of 256 healthy individuals Mexican Mestizo Alaez et al. [[40]]