Table 1.
HLA genotype association | Major findings | Race | References |
---|---|---|---|
HLA-DQA1*0301 |
100% of 57 VKH patients vs. 67.2% of 122 control subjects |
Japanese |
Islam et al. [[24]] |
HLA-DQB1*0604 |
0% of 57 VKH patients vs. 15.6% of 122 control subjects, i.e., may be protective against VKH disease |
Japanese |
Islam et al. [[24]] |
HLA-DRB1*0404 |
25% of 76 VKH patients vs. 9.8% of 256 healthy individuals |
Mexican Mestizo |
Alaez et al. [[40]] |
HLA-DRB1*0405 | 95% of 40 VKH patients vs. 58.2% of DR4-positive healthy controls |
Japanese |
Shindo et al. [[28]] |
54.1% of 37 VKH patients have HLA-DRB1*0405 with a relative risk of 11.76 over the general population |
Highly admixed Brazilian |
Goldberg et al. [[34]] |
|
82.3% of 18 VKH patients vs. 9.3% of 128 control subjects |
Korean |
Kim et al. [[35]] |
|
36.6% of 30 VKH patients vs. 6.9% of 29 control subjects |
Saudi Arabian |
Iqniebi et al. [[36]] |
|
13.2% of 76 VKH patients vs. 0.4% of 256 healthy individuals | Mexican Mestizo | Alaez et al. [[40]] |