Table 2.
Univariate analysis of continuous factors in the modelling set (n = 217)
| Factor | n | Pancreatic fistula | a | P-value | ||
|---|---|---|---|---|---|---|
| No | Yes | AUROC (SE) | ||||
| Patient factor | ||||||
| Age, years, median (IQR) | 217 | 66.7 (59.8–73.4) | 66.9 (60.7–73.3) | 0.502 (0.047) | + | 0.961 |
| BMI, kg/m2, median (IQR) | 211 | 24.7 (22.0–27.0) | 26.8 (24.0–32.4) | 0.677 (0.045) | + | < 0.001 |
| Biochemical result, median (IQR) | ||||||
| White cell count, ×109/l | 216 | 7.70 (6.60–9.80) | 7.90 (6.63–9.48) | 0.508 (0.046) | − | 0.865 |
| Platelet count, ×109/l | 216 | 306 (244–395) | 297 (237–342) | 0.552 (0.046) | − | 0.271 |
| Haemoglobin, g/dl | 216 | 12.6 (11.7–13.5) | 12.6 (11.0–13.7) | 0.506 (0.051) | − | 0.901 |
| International normalized ratio | 212 | 1.00 (1.00–1.10) | 1.00 (0.90–1.10) | 0.516 (0.049) | − | 0.743 |
| Aspartate transaminase, IU/l | 209 | 52.0 (28.0–84.5) | 32.0 (21.3–69.5) | 0.598 (0.048) | − | 0.039 |
| Alanine transaminase, IU/l | 48 | 50.0 (30.3–140.3) | 40.0 (15.8–118.8) | 0.559 (0.115) | − | 0.568 |
| Alkaline phosphatase, IU/l | 216 | 558 (280–955) | 293 (193–672) | 0.630 (0.047) | − | 0.006 |
| Sodium, mmol/l | 216 | 139 (136–142) | 140 (138–142) | 0.548 (0.045) | + | 0.308 |
| Potassium, mmol/l | 213 | 4.30 (3.90–4.60) | 4.20 (3.90–4.47) | 0.529 (0.046) | − | 0.534 |
| Urea, mmol/l | 216 | 5.20 (4.30–6.68) | 5.70 (4.63–7.10) | 0.558 (0.047) | + | 0.220 |
| Creatinine, μmol/l | 216 | 75.0 (64.0–92.8) | 78.5 (66.8–98.5) | 0.567 (0.048) | + | 0.157 |
| Bilirubin, μmol/l | 216 | 39.5 (14.0–130.0) | 14.0 (6.0–50.0) | 0.659 (0.047) | − | 0.001 |
| Albumin, g/l | 216 | 41.0 (38.0–44.0) | 41.0 (38.0–43.0) | 0.502 (0.046) | − | 0.969 |
| Neutrophil count, ×109/l | 216 | 5.00 (3.80–6.60) | 5.30 (4.25–6.35) | 0.523 (0.045) | + | 0.632 |
| Lymphocyte count, ×109/l | 216 | 1.90 (1.40–2.40) | 1.85 (1.30–2.45) | 0.519 (0.047) | − | 0.687 |
| Neutrophil : lymphocyte ratio | 216 | 2.74 (1.91–4.00) | 3.29 (1.66–4.85) | 0.518 (0.049) | + | 0.711 |
| Data from CT imaging, median (IQR) | ||||||
| Pancreas width, mm | 217 | 14.9 (12.7–17.8) | 17.2 (14.3–20.0) | 0.644 (0.044) | + | 0.002 |
| Pancreas duct diameter, mm | 217 | 4.90 (1.75–7.15) | 0.00 (0.00–1.47) | 0.801 (0.033) | − | < 0.001 |
| Renal fat thickness, mm | 217 | 10.0 (4.5–16.1) | 11.5 (6.3–18.8) | 0.581 (0.046) | + | 0.086 |
| Superficial fat thickness, mm | 217 | 13.0 (9.0–19.3) | 14.2 (9.2–24.0) | 0.552 (0.048) | + | 0.276 |
a
+ or − indicates a positive or negative association with pancreatic fistula, respectively.
AUROC, area under the receiver operating characteristic curve; SE, standard error; IQR, interquartile range; BMI, body mass index; CT, computed tomography.