Table 2.
Univariate and multivariate analyses for factors affecting survival in pancreatic ductal adenocarcinoma (PDAC) cases (N = 84)
| Predictor | Level | Hazard ratio | Univariate P-value (log-rank or Wald) | Multivariate P-value (IGFBP2 model) | Multivariate P-value (MSLN model) |
|---|---|---|---|---|---|
| IGFBP2 | – | 1.0015b | < 0.0001 | 0.36a | |
| MSLN | – | 1.015b | 0.022 | 0.29a | |
| Age at Sample | – | 1.031c | 0.0057 | 0.039 | 0.053 |
| Gender | Female | 1.00 | (reference) | (reference) | (reference) |
| Male | 0.5456 | 0.0090 | 0.30 | 0.23 | |
| Class | N0 | (reference) | (reference) | (reference) | |
| N1 | 1.578 | 0.17 | 0.27 | 0.30 | |
| M1 | 6.436 | <0.0001 | <0.0001 | <0.0001 | |
a
Adjusted for age, gender and class.
b
Per unit change.
c
Per year.
Bold numbers indicate statistically significant comparisons.