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. 2014 Jun 25;171(14):3463–3475. doi: 10.1111/bph.12694

Figure 6.

Figure 6

Representative light microscopic images of (scale bar = 200 μm) (A), right ventricular systolic pressure (RVSP) (B), mean arterial blood pressure (MABP) (C), right ventricle : left ventricle plus septum ratio [RV/(LV + S)] (D) and total lung weight (E) in saline controls, bleomycin (BLEO; 1 mg·kg−1)-treated animals, and mice receiving bleomycin in the presence of sildenafil (SILD; 30 mg·kg−1·day−1) plus ecadotril (ECAD; 60 mg·kg−1·day−1). Sildenafil and ecadotril were administered 2 weeks post-bleomycin exposure. #P < 0.05 versus saline control; *P < 0.05 versus bleomycin. n = 6–10 animals in each group.