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. 2014 Jul 22;5:266. doi: 10.3389/fphys.2014.00266

Figure 1.

Figure 1

Schematic representation of a typical ABC protein and characteristic amino acid sequences found in Nucleotide Binding Domains (NBDs). (A) Lipidic bilayer is shown in gray, membrane spanning domains (MSDs) in light brown and nucleotide binding domains (NBDs) in blue, dashed line represents the linker region; (B) aminoacid sequences characteristic from the conserved domains Walker A (x represents any aa), C-motif and Walker-B (Φ represents hydrophobic residues). Adapted from Dean et al. (2001), with permission.