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. Author manuscript; available in PMC: 2014 Jul 22.
Published in final edited form as: Nano Lett. 2012 Oct 25;12(11):5475–5480. doi: 10.1021/nl301865c

Figure 2.

Figure 2

Cell-permeable short-chain C6-ceramide sensitizes Taxol induced cell death in pancreatic cancer cells in vitro. A cell viability MTT assay performed 48 h after treatment confirmed C6-ceramide dramatically sensitizes Taxol induced cell death in three different pancreatic cancer cell lines: (a) L3.6, (b) L3.6, (c) PANC-1, and (d) MIA PaCa-2. Cell death was reflected by reduced cell viability/MTT OD. Note that a relative high concentration of C6-ceramide (5–10 μg/mL) is needed to reach the chemo-sensitization effect. *p < 0.05.