Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 6;11:31. doi: 10.1186/1742-4682-11-31

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Han et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Development of the experimental context-specific quantitative autophagy indices from the minimal model. The workflow of the process is as follows: 1. Establishment of the minimal autophagy model for the target autophagy system. 2. Reconstruction of underlying dynamics of the autophagic process at good time resolution. 3. Introduction of two quantitative autophagy indices measuring autophagy activity based on the model-driven autophagy profile. 4. Computer-aided analysis of the biological data with the help of the indices. 5. Specific/quantitative interpretation and system-level understanding of the system.