Table 4.
Expression levels of genes in up-regulated pathways in the liver (BH vs. BL)
| Pathway | Gene symbol | BH | BL | Probability |
|---|---|---|---|---|
| Metabolism of xenobiotics by cytochrome P450 |
CYP1A2 |
260.26 |
100.93 |
0.83 |
| LOC100515394 |
71.57 |
25.53 |
0.83 |
|
| LOC100526118 |
1539.43 |
574.36 |
0.85 |
|
| CYP1A1 |
81.60 |
29.08 |
0.83 |
|
| LOC100511647 |
3211.75 |
1402.03 |
0.81 |
|
| ADH1A |
2055.82 |
869.66 |
0.82 |
|
| CYP2A6 |
1596.90 |
683.59 |
0.82 |
|
| Drug metism |
CYP1A2 |
260.26 |
100.93 |
0.83 |
| LOC100515394 |
71.57 |
25.53 |
0.83 |
|
| GSTM4 |
192.04 |
66.50 |
0.85 |
|
| LOC100511647 |
3211.75 |
1402.03 |
0.81 |
|
| ADH1A |
2055.82 |
869.66 |
0.82 |
|
| CYP2A6 |
1596.90 |
683.59 |
0.82 |
|
| Retinol metabolism |
CYP1A2 |
260.26 |
100.93 |
0.83 |
| LOC100515394 |
71.57 |
25.53 |
0.83 |
|
| CYP1A1 |
81.60 |
29.08 |
0.83 |
|
| ADH1A |
2055.82 |
869.66 |
0.82 |
|
| CYP2A6 |
1596.90 |
683.59 |
0.82 |
|
| Tryptophan metabolism |
CYP1A2 |
81.60 |
29.08 |
0.83 |
| CYP1A1 |
81.60 |
29.08 |
0.83 |
|
| OGDHL | 6.83 | 0.52 | 0.82 |
Probability: The higher the probability, the greater the change in expression between conditions.
BH, BL: expression level in BH or BL after TMM normalization.