Table.
Treatment |
E3330 |
BSS |
|
CNV lesion area, μm2 | Sum | 537,861 | 958,649 |
Mean | 9,779.29 | 17,429.98 | |
Distribution of CNV size, % | >10,000 μm2 | 41 | 63 |
5000–10,000 μm2 | 21 | 21 | |
<5000 μm2 | 38 | 16 |
The isolectin-stained CNV lesion was quantified by three grades: large (>10000 μm2), medium (5000–10000 μm2), and small (<5000 μm2). The size range was chosen arbitrarily; 56 lesions of 14 choroidal samples were graded for each treatment group. The percent incidence of each category revealed that large-sized CNV proportion was significantly lower in the E3330-treated group than that in the BSS-treated group.