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. 2014 Jun 6;57(13):5602–5619. doi: 10.1021/jm5002277

Table 2. IGABA Modulation through α1β2γ2S GABAA Receptors by Indicated Compounds (100 μM)a.

compd modulation of IGABA (%) n compd modulation of IGABA (%) n
46 42 ± 1** 3 62 13 ± 2 3
47 364 ± 55** 3 63 12 ± 4 3
48 49 ± 7 3 64 4 ± 4 3
49 30 ± 15 3 65 105 ± 18 3
50 178 ± 32* 3 66 67 ± 23 3
51 280 ± 52** 3 67 18 ± 9 3
52 63 ± 12* 3 68 –1 ± 12 3
53 298 ± 31** 3 69 74 ± 1* 3
54 34 ± 8 3 70 32 ± 12 3
55 79 ± 24 3 71 32 ± 10 3
56 114 ± 11 3 72 334 ± 23** 3
57 15 ± 15 3 73 514 ± 76** 3
58 –5 ± 12 3 74 60 ± 17 2
59 134 ± 39 3 75 58 ± 29* 3
60 51 ± 21 3 76 122 ± 26* 3
61 11 ± 2 3 77 138 ± 29* 3
a

All data are given as mean ± SEM. Asterisks indicate significant differences from zero: *p < 0.05, **p < 0.01.