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. Author manuscript; available in PMC: 2014 Jul 22.
Published in final edited form as: Cell. 2006 Feb 10;124(3):495–506. doi: 10.1016/j.cell.2005.12.034

Figure 7. Model for Regulation of MEA Imprinting.

Figure 7

MEA methylation is maintained by MET1. In the central cell, DME removes methylation at the −500 bp region and MEA-ISR. MEA protein is produced and forms PcG complexes. After fertilization, MEA-FIE PcG complexes target the paternal allele to maintain its silent state. Maternal MEA continues to be expressed in the endosperm. Gray box, MEA gene; red circles, DNA methylation; helical line, nontranscribed compacted chromatin; straight line, transcribed open chromatin.