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. Author manuscript; available in PMC: 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16;83(2):331–343. doi: 10.1016/j.neuron.2014.06.016

Figure 1. Progressive, age-dependent deficit in peripheral nerve regeneration.

Figure 1

Cohorts of 2, 12 and 24-month old mice were subjected to sciatic nerve crush injury and restoration of sensory (A) and motor (B) function, assayed through pinprick and toe-spreading assays, respectively. The first day in which a positive sensory (C) or motor (D) behavioral response was also recorded. *P < 0.05; **P < 0.01 in one-way ANOVA with Bonferroni's multiple comparisons test. Mean ± SEM, n = 7–8 mice per cohort.