Table II.

Selected treatment-related toxicities

Toxicity	All Grade No. (%)	Grade 3–5 No. (%)
Non-hematological
Bowel perforation	1 (3)	1 (3)
Diarrhea	21 (70)	5 (17)
Nausea	15 (50)	0
Vomiting	1 (3)	1 (3)
Fatigue	5 (17)	2 (7)
Hand-foot syndrome	7 (23)	0
Hypersensitivity	2 (6)	1 (3)
Hypertension	3 (10)	0
Hypomagnesemia	17 (56)	1 (3)
Paronychia	3 (10)	3 (10)
Proteinuria	6 (20)	0
Sensory neuropathy	25 (84)	8 (27)
Skin rash	27 (90)	11 (37)
Thromboembolism (Arterial)	2 (7)	2 (7)
Thromboembolism (Venous)	2 (7)	2 (7)
Hematological
Anemia	3 (10)	1 (3)
Thrombocytopenia	15 (50)	2 (7)
Neutropenia	10 (33)	0