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. Author manuscript; available in PMC: 2014 Jul 22.
Published in final edited form as: Neuropharmacology. 2009 Feb 5;56(0):956–969. doi: 10.1016/j.neuropharm.2009.01.019

Figure 4. Structure and Pharmacological Profile of the WC Series D3 Receptor Subtype Selective Compounds.

Figure 4

The dissociation constants (nMolar values) for the binding of the D3 receptor selective compounds, WC 10, WC 21, WC 26 and WC 44, to human D2long, D3 and D4.4 dopamine receptors expressed in HEK 293 cells is presented as the mean ± S.E.M. for n ≥ 3 experiments. Values were derived from competitive radioligand binding experiments using 125I-IABN as the radioligand (Luedtke et al., 2000). Affinity and log P values are taken from Chu et al., 2005 and the descriptors in parentheses are how these compounds are designated in that publication.