Table.

Abuse-Deterrent Opioid Formulations

Trade name	Opioid	Mechanism	FDA status
OxyContin	Oxycodone	Hard plastic polymer that renders the tablet difficult to crush or dissolve	Approved in 2010
Remoxy	Oxycodone	Very viscous liquid intended to resist crushing, dissolution, injection, or inhalation	Under FDA review
Suboxone	Buprenorphine	Contains sequestered naloxone (an opioid antagonist), which is released when product is chewed/crushed and cancels the euphoric effects of buprenorphine	Approved in 2002
Embeda	Morphine	Contains sequestered naltrexone (an opioid antagonist), which is released when the product is chewed/crushed and cancels the euphoric effects of morphine	Approved in 2009
Acurox	Oxycodone (immediate release)	Contains an aversive agent (niacin) that causes unpleasant effects when injected, inhaled, or taken orally in high doses	Under FDA review

FDA indicates US Food and Drug Administration.