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. 2010 Sep-Oct;3(5):321–330.

Table 3.

Potential Cost-Savings, Percent Dollars, with 85% or 100% Recommended Drug Utilization

Therapeutic/drug category 85% Recommended filled, % 100% Recommended filled, %
Categories with potential for cost-savings
Antidepressants 70.5 87.2
Statins 16.5 23.0
Proton pump inhibitors 64.0 77.1
Beta-blockers 5.4 12.3
ACE inhibitors 27.4 31.2
Antihistamines 77.5 92.3
Diabetes, oral 39.6 66.9
Insomnia 64.5 79.3
NSAIDs 58.2 84.5
Hormones (estrogenic) 44.6 56.9
Calcium channel blockers 5.3 11.4
ADHD 50.8 62.7
Categories without potential for cost-savings
Migraine -1.0 -3.9
Antipsychotics -27.2 -33.6
Overactive bladder -29.4 -38.2
Alzheimer's disease -9.1 8.9
Total potential cost-savingsa 40.8 51.7
a

Total potential cost-savings was calculated from the sum total cost of all evaluated categories (including those that did not have a potential cost-savings) divided by the sum total of the cost if 85% or 100% of prescriptions were filled with recommended drugs.

ACE indicates angiotensin-converting enzyme; ADHD, attention-deficit/hyperactivity disorder; NSAIDs, nonsteroidal anti-inflammatory drugs.