Table I.

Characteristics of the case-control studies in the current meta-analyses.

Gene	Polymorphism	Authors	Year	Country	Ethnicity	Cases/controls	HWE	Result	Power	(Refs.)
CCK	rs1800857	Zheng et al	2012	China	Asians	508/519	NA	S	0.416	(50)
		Minato et al	2007	Japan	Asians	290/290	Yes	NS	0.321	(51)
		Sanjuan et al	2004	Spain	Europeans	105/93	Yes	NS	0.103	(52)
		Tachikawa et al	2001	Japan	Asians	87/100	Yes	NS	0.138	(53)
CHRNA7	rs904952	Bakanidze et al	2013	German	Europeans	224/224	Yes	S	0.275	(54)
		Bakanidze et al	2013	Georgian	Europeans	50/51	Yes	S	0.099	(54)
		Cabranes et al	2013	Spain	Europeans	152/95	Yes	NS	0.166	(55)
		Ancin et al	2010	Spain	Europeans	508/793	Yes	NS	0.618	(56)
		Iwata et al	2007	China	Asians	188/188	Yes	NS	0.363	(57)
	rs6494223	Cabranes et al	2013	Spain	Europeans	153/95	Yes	NS	0.161	(55)
		Joo et al	2010	Korea	Asians	254/349	NA	S	0.426	(58)
		Ancin et al	2010	Spain	Europeans	510/793	Yes	NS	0.613	(56)
	rs2337506	Bakanidze et al	2013	German	Europeans	224/222	Yes	NS	0.189	(54)
		Joo et al	2010	Korea	Asians	254/349	NA	NS	0.365	(58)
		Iwata et al	2007	China	Asians	188/186	Yes	NS	0.206	(57)
DBH	Ins>Del	Hui et al	2013	China	Asians	195/304	Yes	NS	0.280	(59)
		Zhou et al	2013	China	Asians	747/625	Yes	S	0.655	(60)
		Yamamoto et al	2003	Canada	Europeans	106/120	Yes	NS	0.162	(61)
FEZ1	rs559668	Koga et al	2007	Japan	Asians	1,913/1,911	Yes	NS	0.688	(62)
		Hodgkinson et al	2007	USA	Europeans	159/173	Yes	NS	0.193	(63)
		Yamada et al	2004	Japan	Asians	356/359	Yes	NS	0.164	(30)
	rs597570	Koga et al	2007	Japan	Asians	1,913/1,911	Yes	NS	0.697	(62)
		Hodgkinson et al	2007	USA	Europeans	159/170	Yes	NS	0.172	(63)
		Yamada et al	2004	Japan	Asians	360/359	Yes	NS	0.166	(30)
SNAP25	rs3746544	Lochman et al	2013	Czech	Europeans	183/193	Yes	S	0.212	(47)
		Carroll et al	2009	British Isles	Europeans	650/712	Yes	S	0.615	(48)
		Kawashima et al	2008	Japan	Asians	372/367	NA	S	0.340	(49)
GRIK3	rs6691840	Kilic et al	2010	Turkey	Europeans	256/242	Yes	S	0.240	(64)
		Ahmad et al	2009	India	Asians	100/100	Yes	NS	0.138	(65)
		Lai et al	2005	Taiwan	Asians	160/160	Yes	NS	0.086	(66)
		Begni et al	2002	Italy	Europeans	99/116	Yes	S	0.136	(67)
GCLM	rs2301022	Hanzawa et al	2011	Japan	Asians	358/359	Yes	NS	0.769	(68)
		Ma et al	2010	China	Asians	427/415	NA	S	0.334	(69)
		Kishi et al	2008	Japan	Asians	742/817	Yes	NS	0.344	(70)
		Matsuzawa et al	2009	Japan	Asians	214/220	Yes	NS	0.623	(71)

HWE, Hardy-Weinberg equilibrium; NA, not applicable; S, significant; NS, not significant.