Figure 6.
Alteration of FOXA2 expression in endometrial glands of Tgfbr1 Amhr2-Cre cKO mice. (A–I) Immunofluorescence staining of KRT8 (green) and FOXA2 (red) in control (A–C; 8-month-old) and Tgfbr1 Amhr2-Cre cKO mice at the age of 8 (D–F) and 10.5 (G–I) months. Yellow arrows indicate glandular epithelium. Dotted lines in (D–I) outline cystic dilated glands. Note the absence of FOXA2 in the cystic glands (D–I) and endometrial glands marked with asterisks (F and I). GE, glandular epithelium; LE, luminal epithelium; St, stroma; CG, cystic endometrial gland. Scale bar (50 μm) is representatively shown in (A).