. 2013 Oct 22;29(8):1514–1524. doi: 10.1093/ndt/gft336

Table 1.

Animal characteristics

	Sham	AI
Body mass and heart mass
Body mass (g)	426 ± 9	373 ± 14*
Heart mass (g)	1.49 ± 0.06	1.70 ± 0.04*
Tibia length (cm)	4.3 ± 0.08	4.4 ± 0.07
Heart mass × tibia length⁻¹ (mg/mm)	35 ± 1.3	39 ± 1.1*
Renal function
Serum creatinine (mg/dl)	0.5 ± 0.06	2.5 ± 0.4*
Urine flow rate (ml × 24 h⁻¹ × 100 g of body mass⁻¹)	3.0 ± 0.4	8.2 ± 0.9*
Protein excretion (mg × 24 h⁻¹ × 100 g of body mass⁻¹)	5.8 ± 0.6	41.5 ± 4.9*
Renal pathology
Glomerulosclerosis Index Score	0.16 ± 0.03	3.0 ± 0.17*
% Normal glomeruli (grade 0)	90.2 ± 2.8	2.9 ± 1.2*
% Minimal-to-moderate sclerosis (grades 1–2)	9.6 ± 2.8	28.6 ± 4.7*
% Moderate-to-severe sclerosis (grades 3–4)	0.2 ± 0.2	68.5 ± 5.8*

Characteristics of the Sham and AI animals including body mass and heart mass (sham n = 16, AI n = 16) as well as renal function (serum creatinine: sham n = 7, AI n = 7; urine flow rate and protein excretion: sham n = 14, AI n = 14) and pathology (sham n = 5, AI n = 5). Values are mean ± SEM. AI: 5/6 ablation–infarction rats;

*P < 0.05 versus sham.