Representative immunohistochemical staining of (A-D) cyclooxygenase-2 and (E-H) p27 in lung cancer tissues obtained from the patients in this study. (A and E) 0, no expression; (B and F) 1+, weak expression; (C and G) 2+, moderate expression; and (D and H) 3+, strong expression. Scale bars, 250 μm.