Skip to main content
. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Fertil Steril. 2014 Apr 30;101(6):1574–81.e1-2. doi: 10.1016/j.fertnstert.2014.03.012

Table 3.

Number (%) of couples initiating treatment cycles, total number of cycles initiated, and pregnancy rates by treatment group per initiated cycle and per couple who initiated treatment, separately for the first two cycles of treatment and subsequent IVF treatments.

Randomized treatment arm and treatment type No. couples who initiated treatment (%) No. cycles initiated Clinical pregnancy ratesa Live birth rates
No. Per cycle %, 97.5% CI Per couple %, 97.5% CI No. Per cycle %, 97.5% CI Per couple %, 97.5% CI
CC/IUI (n = 51)
 CC/IUI 45 (88.2) 87 6 6.9, 2.5–17.7b 13.3, 4.3–28.8b 3 3.4, 0.7–16.1b 6.7, 1.1–20.1b
 IVF 39 (86.7) 95 21 22.1, 13.0–35.0 53.8, 38.5–68.5 15 15.8, 7.9–29.1 38.5, 21.6–57.6
  Total 182 27 14.8, 9.7–22.1 60.0, 42.3–76.0 18 9.9, 5.5–17.0 40.0, 24.0–57.7
FSH/IUI (n = 52)
 FSH/IUI 48 (92.3) 91 7 7.7, 2.8–19.6c 14.6, 5.3–29.7c 6 6.6, 2.1–18.9c 12.5, 4.0–27.1c
 IVF 37 (77.1) 96 24 25.0, 14.7–39.1 64.9, 45.2–81.5 15 15.6, 7.5–29.6 40.5, 24.8–57.9
  Total 187 31 16.6, 11.0–24.3 64.6, 47.4–79.4 21 11.2, 6.3–19.1 43.8, 27.7–60.8
Immediate IVF (n = 51)
 1st 2 IVF 47 (92.2) 85 21 24.7, 16.1–35.7 44.7, 28.4–61.9 13 15.3, 7.6–28.3 27.7, 14.3–44.7
 ≥ 3rd IVF 23 (48.9) 33 8 24.2, 10.5–46.6 34.8, 14.5–60.1 5 15.2, 4.5–40.4 21.7, 6.3–46.7
  Total 118 29 24.6, 16.1–35.7 61.7, 44.4–77.1 18 15.3, 8.2–26.7 38.3, 22.9–55.7
All treatment initiated 140 (90.9) 487 87 17.9, 14.3–22.1 62.1, 52.4–71.3 57 11.7, 8.8–15.4 40.7, 31.8–50.2

Abbreviations: CC = Clomiphene citrate; FSH = Gonadotropins; IUI = Intrauterine insemination; IVF = In vitro fertilization.

Note: For IVF treatment cycles, 2 of the cycles in the CC/IUI arm, 2 of the cycles in the FSH/IUI arm, and 3 of the cycles in the immediate IVF arm used cryopreserved embryos that had been collected in an earlier cycle and frozen for use in subsequent cycles.

a

Number of clinical pregnancies includes all ultrasound confirmed pregnancies, including pregnancy losses.

b

P values for comparison between CC/IU vs. 1st 2 immediate IVF cycles: P = 0.0015 for clinical pregnancy rate per cycle; P=0.0012 for clinical pregnancy rate per couple; P=0.0085 for live birth rate per cycle; P=0.0119 for live birth rate per couple.

c

P values for comparison between FSH/IUI vs. 1st 2 immediate IVF cycles: P=0.0033 for clinical pregnancy rate per cycle; P=0.0016 for clinical pregnancy per couple; P=0.09 for live birth rate per cycle; P=0.08 for live birth rate per couple.