Table V.
CTCAE ver. 3.0 grade | BBP− (n=27) | BBP+ (n=15) | ||||||||||
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1, n | 2, n | 3, n | 4, n | All, % | ≥G3, % | 1, n | 2, n | 3, n | 4, n | All, % | ≥G3, % | |
Leucopenia | 4 | 2 | 1 | 0 | 25.9 | 3.7 | 1 | 6 | 1 | 1 | 60.0 | 13.3 |
Neutropenia | 1 | 3 | 2 | 0 | 22.2 | 7.4 | 1 | 6 | 1 | 1 | 60.0 | 13.3 |
Anemia | 5 | 2 | 3 | 0 | 37.0 | 11.1 | 4 | 1 | 0 | 0 | 33.3 | 0.0 |
Thrombocytopenia | 4 | 0 | 0 | 0 | 14.8 | 0.0 | 3 | 1 | 0 | 0 | 26.7 | 0.0 |
Diarrhea | 5 | 8 | 2 | 0 | 55.6 | 7.4 | 5 | 2 | 0 | 0 | 46.7 | 0.0 |
Anorexia | 3 | 7 | 2 | 0 | 44.4 | 7.4 | 5 | 2 | 0 | 0 | 46.7 | 0.0 |
Nausea | 5 | 7 | 0 | 0 | 44.4 | 0.0 | 4 | 4 | 0 | 0 | 53.3 | 0.0 |
Vomiting | 1 | 6 | 0 | 0 | 25.9 | 0.0 | 3 | 0 | 0 | 0 | 20.0 | 0.0 |
Fatigue | 2 | 4 | 2 | 0 | 29.6 | 7.4 | 3 | 1 | 0 | 0 | 26.7 | 0.0 |
Stomatitis | 1 | 0 | 0 | 0 | 3.7 | 0.0 | 1 | 0 | 0 | 0 | 6.7 | 0.0 |
Dizziness | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 |
Neuropathy | 8 | 2 | 0 | 0 | 37.0 | 0.0 | 4 | 1 | 0 | 0 | 33.3 | 0.0 |
Alopecia | 5 | 5 | 1 | 0 | 40.7 | 3.7 | 3 | 6 | 0 | 0 | 60.0 | 0.0 |
Hand-foot syndrome | 6 | 1 | 0 | 0 | 25.9 | 0.0 | 3 | 0 | 1 | 0 | 26.7 | 6.7 |
Proteinuria | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 |
Hypertension | 0 | 1 | 2 | 0 | 11.1 | 7.4 | 2 | 3 | 3 | 0 | 53.3 | 20.0 |
Bleeding | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 |
BBP, bevacizumab beyond progression; CTCAE, Common Terminology Criteria for Adverse Events.