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. 2014 Jun 25;2(5):798–804. doi: 10.3892/mco.2014.328

Table IV.

Preoperative predictive factors for postoperative extrahepatic recurrence on univariate and multivariate regression models.

Univariate analysis Multivariate analysis


Parameters Hazard ratio (95% CI) P-value Hazard ratio (95% CI) P-value AUC
Age (years) 1.01 (0.95–1.09) 0.641
BMI (kg/m2) 1.04 (0.88–1.20) 0.584
AST (IU/l) 1.01 (0.99–1.04) 0.122
ALT (IU/l) 1.01 (0.99–1.03) 0.158
PLT (x104/μl) 1.04 (0.94–1.14) 0.414
TBil (mg/dl) 1.45 (0.28–5.22) 0.593
Alb (g/dl) 1.46 (0.42–6.08) 0.573
PT (%) 1.00 (0.95–1.04) 0.854
AFP (ng/ml) 1.00 (1.00–1.00) 0.019 1.00 (1.00–1.00) 0.125
PIVKA-II (mAU/ml) 1.00 (1.00–1.00) 0.012 1.00 (0.99–1.00) 0.387
HbA1c (%) 0.55 (0.16–1.52) 0.286
Diameter of tumor (cm) 1.19 (1.01–1.42) 0.033 0.93 (0.64–1.20) 0.620
SUVmax 1.26 (1.03–1.53) 0.001 1.24 (1.01–1.55) 0.033 0.846

CI, confidence interval; AUC, area under the receiver operating characteristic curve; BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; PLT, platelet count; TBil, total bilirubin; Alb, albumin; PT, prothrombin time; AFP, α-fetoprotein; PIVKA-II, protein induced by vitamin K absence or antagonist-II; HbA1c, hemoglobin A1c; SUVmax, maximal standardized uptake value.