Table 2. Characteristics of EEG and seizures.
Neonate | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
Summary of background EEG feature | |||||||||
Continuous activity | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
Symmetry | Left mild suppression | Left significant suppression | Right mild suppression | Good | Right mild suppression | Good | Good | Left significant suppression | Right mild suppression |
Intermittent features | Left-sided sharp theta bursts | Left-sided theta sharp waves | Right focal sharp waves | Left-sided sharp waves in quiet sleep | Right-sided theta sharp waves | Left-sided theta sharp waves | Left-sided focal sharp theta waves | Left-sided theta sharp waves | Right-sided sharp waves |
Sleep cycling | Normal bilaterally | Disturbed unilaterally | Disturbedbilaterally | Disturbed bilaterally | Normal bilaterally | Normal bilaterally | Disturbed unilaterally | Disturbed unilaterally | Normal bilaterally |
Seizure morphology | Focal spikes over left central with phase reversal | Focal spikes over left central with phase reversal | Focal spikes over right central with phase reversal | Focal spikes & polyspikes over left central with phase reversal | Focal spikes & polyspikes over right central with phase reversal | Focal spikes over left central with phase reversal | Focal spikes over left central with phase reversal | Focal spikes & polyspikes over left central with phase reversal | Focal spikes & polyspikes over right central with phase reversal |
Summary of seizure burden | |||||||||
Total seizure burden (minutes) | 19 | 67 | 101 | 133 | 162 | 201 | 266 | 327 | 332 |
Seizure burden (minutes/hour) | 2.70 | 7.28 | 27.60 | 5.53 | 10.27 | 18.15 | 12.77 | 9.25 | 6.18 |
Mean seizure duration (seconds) | 370 | 98 | 356 | 362 | 120 | 523 | 143 | 195 | 146 |
Seizure window (hours) | 7 | 9 | 4 | 24 | 16 | 11 | 21 | 35 | 54 |
Status epilepticus | None | None | Yes | None | None | Yes | Yes | Yes | Yes |
Number of seizures (n) | 3 | 41 | 17 | 22 | 81 | 23 | 112 | 101 | 136 |
Seizure classification | |||||||||
Electrographic-only seizures: n (%) | 0 (0) | 27 (66) | 8 (47) | 20 (91) | 77 (95) | 13 (57) | 77 (69) | 62 (61) | 121 (89) |
Electrographic-only seizure burden: minutes (%) | 0 (0) | 28 (42) | 26 (25) | 129 (97) | 146 (90) | 74 (37) | 129 (49) | 244 (74) | 282 (85) |
Electroclinical seizures: n (%) | 2 (66) | 10 (24) | 7 (41) | 1 (4.5) | 3 (3.7) | 9 (39) | 32 (29) | 35 (35) | 15 (11) |
Electroclinical seizure burden: minutes (%) | 18 (95) | 30 (44) | 48 (48) | 3 (2) | 15 (9) | 108 (54) | 126 (47) | 80 (24) | 50 (15) |
Clonic/subtle seizures: n | 2/0 | 0/10D | 5/2C | 1/0 | 3/0 | 0/9S | 17/15S | 16/19Y | 9/6M |
Video obscured: n (%) | 1 (33) | 4 (10) | 2 (12) | 1 (4.5) | 1 (1.3) | 1 (4) | 3 (2) | 4 (4) | 0 (0) |
Subtle seizures: C, cycling movements of the limbs; D, desaturations; M, mouthing and smacking; S, sucking; Y, yawning.