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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: NMR Biomed. 2014 Apr 6;27(6):663–671. doi: 10.1002/nbm.3103

Figure 1.

Figure 1

(a) Schematic Pulse sequence for time dependent magnetization transfer using 1D-ISIS localization. The selective spectral saturation is achieved by a low power RF pulse centered on the γ-ATP resonance. Saturation times are varied by looping over the saturation pulse with 1 ms gap between the successive pulses. An adiabatic full passage pulse immediately follows the saturation pulse train for ISIS localization. Spoiling gradients are used before excitation to disperse any residual transverse magnetization.