Skip to main content
. 2014 Jul 22;9(7):e101602. doi: 10.1371/journal.pone.0101602

Figure 3. A–C. Quantification of Subretinal NV in Various Control and Experimental Groups.

Figure 3

Metamorph image-analysis software was used to compute the number and area of neovascular lesions and the total area of NV on the outer surface of each retina. The figure displays; A) the number of NV lesions per retina; B) the total neovascular area per retina; and C) the average neovascular lesion per retina. Mice that were treated with YC-1 and SN50 had; 1) significantly fewer neovascular lesions, 2) significantly smaller NV area per retina, and 3) smaller area of NV lesion per retina, than did mice that were treated with DMSO and SN50M, respectively. Image analysis confirmed that there was no difference between DMSO- and SN50M-treated mice and mice that were left untreated.