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. 2014 Jul 22;9(7):e102233. doi: 10.1371/journal.pone.0102233

Table 6. Changes in Amino Acid Levels of HIV-infected (surviving) and HIV-negative patients.

HIV-infected (n = 10) HIV-negative (n = 44)
Mean±SEM p-value Mean±SEM p-value
Admission 14-day Admission 14-day
Glycine (µmol/L) 216±16.6 313±28.1 0.0020 238±13.7 305±13.4 <0.0001
Alanine 150±18.1 409±57.7 0.0020 218±18.6 418±27.5 <0.0001
Serine 98.8±4.5 125±14.6 0.0371 113±6.4 157±6.9 <0.0001
Proline 155±14.5 296±42.6 0.0098 152±9.4 282±20.3 <0.0001
Valine 102±15.8 130±21.3 0.375 76.8±6.2 152±10.2 <0.0001
Leucine/Isoleucine 80.1±15.0 112±15.2 0.106 71.0±5.2 132±7.3 <0.0001
Methionine 16.8±2.8 19.7±3.3 0.193 15.6±1.0 24.5±1.6 <0.0001
Histidine 64.5±12.7 53.9±5.7 0.432 52.8±3.4 50.7±2.7 0.954
Phenylalanine 78.4±18.2 59.8±5.3 0.432 43.3±2.8 53.0±2.5 0.0184
Tyrosine 29.8±7.2 45.8±10.6 0.0840 22.6±2.7 52.1±5.0 <0.0001
Aspartate 31.3±6.3 50.4±10.5 0.0039 35.4±2.7 51.0±5.0 <0.0001
Glutamate 109±12.7 135±17.3 0.275 91.3±4.7 152±8.2 <0.0001
Ornithine 29.3±3.1 40.2±6.8 0.0195 26.7±2.3 47.9±3.3 <0.0001
Citrulline 8.9±1.1 16.3±3.4 0.0098 8.3±0.7 19.0±1.6 <0.0001
Arginine 29.2±2.4 44.5±6.9 0.0137 27.8±2.2 49.7±3.3 <0.0001