Table 2. Accuracy of Xpert MTB/Rif test on pleural fluid in pleural TB diagnosis using pleural tissue MTB culture and/or histopathology as reference standard, stratified by HIV status.

	Overall accuracy, N = 116, Estimated (95% CI)	HIV-uninfected, N = 64, Estimate (95% CI)	HIV-infected, N = 52, Estimate (95% CI)
Sensitivity	28.7% (19.5%, 39.4%)	21.7% (10.9%, 36.4%)	36.6% (22.1%, 53.1%)
Specificity	96.6% (82.2%, 99.9%)	100.0% (81.5%, 100.0)%	90.9% (58.7%, 99.8%)
PPV	96.1% (80.4%, 99.9%)	100.0% (69.1%, 100.0%)	93.8% (69.8%, 99.8%)
NPV	31.1% (21.8%, 41.7%)	33.3% (21.1%, 47.5%)	27.8% (14.2%, 45.2%)

Abbreviations: PPV, positive predictive value; NPV, negative predictive value; CI, confidence intervals; N, number of participants.