Table 3. The correlations between hemodialysis type, uremic toxins, and inflammatory markers.
Vascular access | Synthetic membrane use | High flux dialysis | Total IS | Total PCS | hs-CRP | IL-1β | IL-6 | TNF-α | |
Vascular access | — | −0.125 | −0.101 | −0.122 | −0.083 | −0.093 | −0.046 | 0.049 | −0.043 |
Synthetic membrane use | −0.125 | — | 0.865*** | 0.195*** | −0.029 | −0.060 | −0.016 | −0.106 | −0.082 |
High flux dialysis | −0.101 | 0.865*** | — | 0.159** | −0.052 | −0.028 | 0.005 | −0.065 | 0.089 |
Total IS (mg/L) | −0.122 | 0.195*** | 0.159** | — | 0.292*** | −0.011 | 0.013 | −0.062 | −0.062 |
Total PCS (mg/L) | −0.083 | −0.029 | −0.052 | 0.292*** | — | 0.039 | −0.102 | 0.074 | 0.093 |
hs-CRP (mg/L) | −0.093 | −0.060 | −0.028 | −0.011 | 0.039 | — | −0.033 | 0.407*** | 0.264*** |
IL-1β (ng/L) | −0.046 | −0.016 | 0.005 | 0.013 | −0.102 | −0.033 | — | 0.004 | −0.022 |
IL-6 (ng/L) | 0.049 | −0.106 | −0.065 | −0.062 | 0.074 | 0.407*** | 0.004 | — | 0.478*** |
TNF-α (ng/L) | −0.043 | −0.082 | 0.089 | −0.062 | 0.093 | 0.264*** | −0.022 | 0.478*** | — |
*p value<0.1.
** p value<0.05.
***p value<0.01.
Abbreviations: IS, indoxyl sulfate; PCS: p-cresol sulfate; hs-CRP, high sensitive C-reactive protein; IL-1β, interleukin −1 beta; IL-6, interleukin 6; TNF-α, tumor necrosis factor- alpha.