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. 2014 Jul 22;9(7):e102691. doi: 10.1371/journal.pone.0102691

Table 3. The correlations between hemodialysis type, uremic toxins, and inflammatory markers.

Vascular access Synthetic membrane use High flux dialysis Total IS Total PCS hs-CRP IL-1β IL-6 TNF-α
Vascular access −0.125 −0.101 −0.122 −0.083 −0.093 −0.046 0.049 −0.043
Synthetic membrane use −0.125 0.865*** 0.195*** −0.029 −0.060 −0.016 −0.106 −0.082
High flux dialysis −0.101 0.865*** 0.159** −0.052 −0.028 0.005 −0.065 0.089
Total IS (mg/L) −0.122 0.195*** 0.159** 0.292*** −0.011 0.013 −0.062 −0.062
Total PCS (mg/L) −0.083 −0.029 −0.052 0.292*** 0.039 −0.102 0.074 0.093
hs-CRP (mg/L) −0.093 −0.060 −0.028 −0.011 0.039 −0.033 0.407*** 0.264***
IL-1β (ng/L) −0.046 −0.016 0.005 0.013 −0.102 −0.033 0.004 −0.022
IL-6 (ng/L) 0.049 −0.106 −0.065 −0.062 0.074 0.407*** 0.004 0.478***
TNF-α (ng/L) −0.043 −0.082 0.089 −0.062 0.093 0.264*** −0.022 0.478***

*p value<0.1.

** p value<0.05.

***p value<0.01.

Abbreviations: IS, indoxyl sulfate; PCS: p-cresol sulfate; hs-CRP, high sensitive C-reactive protein; IL-1β, interleukin −1 beta; IL-6, interleukin 6; TNF-α, tumor necrosis factor- alpha.