Table 2. Distribution of FMR1 genotype and sub-genotype in sporadic POF patients.

		Allele-1	Allele-2	POF (n = 379)
norm		26–34	26–34	256 (67.5%)
het	het-norm/low	<26	26–34	20 (5.3%)
	het-norm/high	26–34	>34	90 (23.7%)
	Total			110 (29.0%)
hom	hom-low/low	<26	<26	1 (0.3%)
	hom-high/high	>34	>34	9 (2.4%)
	hom-low/high	<26	>34	3 (0.8%)
	Total			13 (3.5%)

Note: By definition allele 1 has the lowest number of repeats. norm: both alleles within normal range; het: one allele within normal range and the other allele outside; hom: both alleles outside normal range.