Table 3. Comparation of the CGG repeats on FMR1 gene between sporadic POF patients and normal control women.
POF (n = 379) | Control (n = 402) | P-value | |
Allele-1 | 29.7 (29.5–30.0) | 28.8 (28.6–29.0) | <0.001a |
Allele-2 | 32.6 (32.1–33.1) | 31.5 (31.1–31.8) | <0.001a |
Unaffected(≤40; n%) | 366(96.6) | 395(98.3) | 0.174b |
Intermediate (41–54; n%) | 11(2.9) | 7(1.7) | 0.343b |
Premutation (55–200; n%) | 2(0.5) | 0 | - |
Full mutation (>200; n%) | 0 | 0 | - |
Note: P-value was obtained by Mann-Whitney Testa or Pearson chi-square testb between POF and Control.