Table 2. Genotype and allele frequencies of variants in the TNFAIP3 promoter in healthy controls and AP patients.
| Healthy controls | AP patients | SAP patients | p-value | OR | 95% CI | |
| rs5029924 | ||||||
| Genotypes | ||||||
| CC | 155 (77.1%) | 135 (71.1%) | 41(67.2%) | |||
| CT+TT | 46 (22.9%) | 55 (28.9%) | 20(32.8%) | 0.171a | 1.373a | 0.871–2.163a |
| 0.119b | 1.644b | 0.877–3.079b | ||||
| CT | 44 (21.9%) | 52 (27.3%) | 19(31.1%) | |||
| TT | 2 (1.0%) | 3 (1.6%) | 1(1.7%) | |||
| Alleles | ||||||
| C | 354 (88.1%) | 322 (84.7%) | 101(82.8%) | |||
| T | 48 (11.9%) | 58 (15.3%) | 21(17.2%) | 0.175a | 1.328a | 0.881–2.004a |
| 0.131b | 1.533b | 0.877–2.680b | ||||
| rs59693083 | ||||||
| Genotypes | ||||||
| AA | 139 (69.2%) | 129 (67.9%) | 42(68.9%) | |||
| AG+GG | 62 (30.8%) | 61 (32.1%) | 19(31.1%) | 0.789a | 1.060a | 0.692–1.625a |
| 0.495b | 1.228b | 0.681–2.215b | ||||
| AG | 56 (27.9%) | 56 (29.5%) | 15(24.6%) | |||
| GG | 6 (2.9%) | 5 (2.6%) | 4(6.5%) | |||
| Alleles | ||||||
| A | 334 (83.1%) | 314 (82.6%) | 99(81.1%) | |||
| G | 68 (16.9%) | 66 (17.4%) | 23(18.9%) | 0.867a | 1.032a | 0.712–1.498a |
| 0.835b | 0.943b | 0.541–1.643b | ||||
AP indicates acute pancreatitis; SAP indicates severe AP; CI indicates confidence interval; OR indicates odds ratio;
a
indicates AP patients compare with healthy controls;
b
indicates SAP patients compare with healthy controls.