Skip to main content
. Author manuscript; available in PMC: 2014 Jul 22.
Published in final edited form as: J Med Chem. 2012 Sep 20;55(19):8272–8282. doi: 10.1021/jm300371c

Figure 4.

Figure 4

Time activity curves (TACs) from mouse positron emission tomography (PET) studies. TACs represent accumulation of [18F]13 in whole mouse brain as a function of time for baseline (n=3), pre block with 2 (n=3), pre block with 13 (n=3), and pre block with 18 (n=3). Baseline studies involved iv administration of [18F]13 (95-125 μCi), whereas blocking studies involved pre-treatment of mice with either 2 (1 mg/kg), 13 (1 mg/kg) or 18 (1 mg/kg) 10 min prior to iv administration of [18F]13 (95-125 μCi).