Figure 6. G:C content surrounding HIV integration sites.

The percentage of HIV integration sites compared to the percentage of G:C base pairs within a 5 kb window is shown for wild type cells compared to (A) OGG1 null cells, (B) MYH null cells, (C) wild type cells treated with 10 µM H₂O₂, and (D) wild type cells treated with 30 µM H₂O₂. The frequency of G:C base pairs in the mouse genome is 0.41. There is no significant difference between HIV integration sites in untreated wild type cells and OGG1 null (p = 0.96), MYH null (p = 0.99), 10 µM H₂O₂ treated (p = 0.67), or 30 µM H₂O₂ treated cells (p = 0.88).