Figure 2.

Characteristics of β-CD-(D₃)₇/MMP-9-siRNA complexes

Notes: (A) Electrophoretic mobility of MMP-9-siRNA in β-CD-(D₃)₇/MMP-9-siRNA at various N/P ratios. The arrow indicates the uncombined siRNA; the arrowhead indicates the siRNA trapped in the well. (B) Particle size of β-CD-(D₃)₇/MMP-9-siRNA complexes at various N/P ratios. (C) Representative TEM image (inset) and particle size distribution for the β-CD-(D₃)₇/MMP-9-siRNA complexes at the N/P ratio of 30.

Abbreviations: β-CD-(D₃)₇, a cationic star-shaped polymer consisting of a β-cyclodextrin core and poly(amidoamine) dendron arms; MMP-9, matrix metalloproteinase-9; N/P, amino group to phosphate group; siRNA, small interfering RNA; TEM, transmission electron microscopy.