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. 2014 Jul 15;9:3377–3387. doi: 10.2147/IJN.S66368

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© 2014 Li et al. This work is published by Dove Medical Press Ltd, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Ltd, provided the work is properly attributed.

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Typical fluorescence images of fibroblast cells after 12 hours’ incubation.

Notes: Cells were incubated with (A) β-CD-(D₃)₇/MMP-9-siRNA complexes at the mass ratio of 20; (B) β-CD-(D₃)₇/MMP-9-siRNA complexes at the mass ratio of 4; or (C) Lipofectamine^® 2000/MMP-9-siRNA complexes at the mass ratio of 20. Lipofectamine 2000 was purchased from Thermo Fisher Scientific (Waltham, MA, USA).

Abbreviations: β-CD-(D₃)₇, a cationic star-shaped polymer consisting of a β-cyclodextrin core and poly(amidoamine) dendron arms; MMP-9, matrix metalloproteinase-9; siRNA, small interfering RNA.