Mice were subjected to sham surgery or cecal ligation and puncture (CLP) to induce sepsis. Plasma concentrations of ATP (A), ADP (B), AMP (C), and adenosine (D) were assessed by HPLC before (0 h) and at the indicated time points after sham surgery or CLP (n=7 for each data point, mean ± SEM, Unpaired t-test, *p<0.05, **p<0.01).