Skip to main content
. Author manuscript; available in PMC: 2015 Jul 14.
Published in final edited form as: Angew Chem Int Ed Engl. 2014 May 30;53(29):7524–7530. doi: 10.1002/anie.201403500

Figure 1.

Figure 1

Chemical structures of HSAF and other PTM analogs and HPLC analysis of the HSAF analogs produced in Streptomyces. SR107, metabolites from non-transformed Streptomyces sp. LZ35 strain SR107, in which four native PKS gene clusters had been deleted; SR107HSAF, metabolites from strain SR107HSAF1 transformed with the PKS-NRPS biosynthetic gene cluster under the control of ermE* promoter. The first two HPLC profiles show the metabolites detected at 380 nm, and the bottom two show the metabolites detected at 318 nm. The asterisks indicate peaks that were absent in the control.