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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Neuropharmacology. 2014 Jun 2;85:243–252. doi: 10.1016/j.neuropharm.2014.05.033

Table 2. Induction of Conditioning and Sensitization: mKal7.

Outline of one of the 4 conditioning days used to expose rats to their respective injections during transient HSV infection in the HSV-mKal7 experiment. One day before this 4-day exposure phase, rats received bilateral HSV-mKal7 or Mock (HSV-GFP or 1X PBS) infusions into the NAcc. During exposure, saline (1.0 ml/kg) and amphetamine (1.5 mg/kg) were administered IP. On each of the 4 conditioning days, rats received an injection in either the open field or the home cage in one session and an injection in the opposite location five hours later. Session order was counterbalanced each day. Following a 1-week withdrawal period, rats were then tested for conditioning (following a saline injection; 1.0 ml/kg, IP) and five days later for sensitization (following an amphetamine injection; 1.0 mg/kg, IP).

Group Day 1
Open Field Home Cage
Paired-Mock
n=5 		Amphetamine Saline
Paired-mKal7
n=6 		Amphetamine Saline
Unpaired-Mock
n=5 		Saline Amphetamine
Unpaired-mKal7
n=5 		Saline Amphetamine
Control-Mock
n=5 		Saline Saline
Control-Mock
n=5 		Saline Saline