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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: J Thromb Haemost. 2014 Jun 19;12(7):1121–1130. doi: 10.1111/jth.12600

Figure 3. Plasma clot stability correlates with bleeding risk in FXI-deficient patients.

Figure 3

Clotting was triggered by recalcification and addition of TF and phospholipids in the presence of t-PA in a blinded fashion. Clot formation and lysis were monitored by turbidity. A) Representative clot formation and lysis curves. B–F) Values for: B) rate (Vmax), C) time to peak turbidity, D) lysis time, E) peak turbidity change, and F) area under the clotting curve for plasmas from controls and FXI-deficient patients (non-bleeders and bleeders, as indicated). The boxes enclose 50% of the data with the median value displayed as a horizontal line, and lines enclose the IQD. Open symbols represent points whose value falls more than 1.5-fold outside the IQD.