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Thrombin generation parameters
| Controls (n=9) | Non-bleeders (n=8) | Bleeders (n=8) | P ANOVA | P Controls vs Non-Bleeders | P Controls vs Bleeders | P Bleeders vs Non-Bleeders | |
|---|---|---|---|---|---|---|---|
| Lagtime (minutes) | 4.2 ± 1.2 | 5.1 ± 1.7 | 4.9 ± 1.0 | 0.37 | – | – | – |
| Time to peak (minutes) | 9.5 ± 2.4 | 11.4 ± 2.9 | 10.8 ± 2.4 | 0.32 | – | – | – |
| Thrombin Peak (nM) | 86.1 ± 59.7 | 57.1 ± 26.3 | 57.6 ± 41.5 | 0.33 | – | – | – |
| ETP (nM*minutes) | 809 ± 387 | 789 ± 319 | 684 ± 394 | 0.76 | – | – | – |
Mean±SD
