Table 8.
Genetic correlations (Pearson r) between activity phenotypes during habituation and conditioning.
| Phenotype* | HAB -0 |
HAB- 2 |
HAB- 4 |
S1-0 | S1-2 | S1-4 | S4-0 | S4-2 | S4-4 | (S4- HAB)- 0 |
(S4- HAB)- 2 |
(S4- HAB)- 4 |
E1-2 | E1-4 | (E1- S1)-2 |
(E1- S1)-4 |
E4-2 | E4-4 | (E4- S4)-2 |
(E4- S4)-4 |
Tol/Se ns-2 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HAB-0 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| HAB-2 | .97d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| HAB-4 | .98d | .99d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| S1-0 | .87d | .90d | .87d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| S1-2 | .79c | .86d | .83d | .96d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| S1-4 | .85d | .92d | .89d | .97d | .97d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| S4-0 | .60a | .61a | .60a | .75b | .68b | .71b | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| S4-2 | .60a | .64a | .64a | .84d | .82c | .81c | .87d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| S4-4 | .63a | .64a | .65a | .80c | .74b | .76b | .88d | .94d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| (S4-HAB)-0 | −.87d | −.83d | −.84d | −.61a | −.56a | −.63a | −.14 | −.22 | −.25 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| (S4-HAB)-2 | −.82c | −.83d | −.82c | −.56a | −.53a | −.61a | −.17 | −.10 | −.15 | .92d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| (S4-HAB)-4 | −.86d | −.87d | −.88d | −.62a | −.61a | −.67b | −.22 | −.23 | −.21 | .93d | .96d | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| E1-2 | .56a | .58a | .56a | .74b | .73b | .75b | .57a | .73b | .74b | −.35 | −.22 | −.25 | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| E1-4 | .57a | .59a | .58a | .64a | .54a | .59a | .49 | .57a | .74b | −.41 | −.35 | -.28 | .67b | -- | -- | -- | -- | -- | -- | -- | -- |
| (E1-S1)-2 | .22 | .19 | .19 | .34 | .31 | .35 | .31 | .44 | .51 | −.09 | .07 | .08 | .87d | .55a | -- | -- | -- | -- | -- | -- | -- |
| (E1-S1)-4 | −.08 | −.12 | −.10 | −.10 | −.22 | −.18 | −.05 | −.04 | .22 | .07 | .13 | .27 | .14 | .68b | .35 | -- | -- | -- | -- | -- | -- |
| E4-2 | .17 | .22 | .22 | .51 | .55a | .51 | .59a | .83c | .75b | .15 | .31 | .19 | .72b | .35 | .61a | -.03 | -- | -- | -- | -- | -- |
| E4-4 | .41 | .48 | .49 | .67b | .66b | .62a | .62a | .79c | .87d | −.14 | −.05 | −.08 | .68b | .77c | .47 | .38 | .75b | -- | -- | -- | -- |
| (E4-S4)-2 | −.06 | .00 | .00 | .30 | .36 | .31 | .39 | .65b | .57a | .31 | .46 | .36 | .62a | .21 | .62a | −.02 | .96d | .64b | -- | -- | -- |
| (E4-S4)-4 | .11 | .21 | .21 | .37 | .42 | .34 | .22 | .46 | .53a | .00 | .06 | .06 | .45 | .61a | .33 | .43 | .57a | .88d | .56a | -- | -- |
| Tol/Sens-2 | −.29 | −.18 | −.18 | .05 | .15 | .06 | .20 | .39 | .23 | .47 | .51 | .38 | −.05 | −.26 | −.18 | −.37 | .62 | .35 | .66b | .38 | -- |
| Tol/Sens-4 | .16 | .28 | .26 | .38 | .55a | .45 | .21 | .38 | .16 | −.08 | −.09 | −.24 | .19 | −.27 | −.13 | −.74b | .46 | .25 | .44 | .28 | .67b |
d= p < 0.0001, c= p < 0.001, b= p < 0.01, a= p < 0.05
*
The suffix (−0, −2, −4) indicates the ethanol dose group; HAB = habituation day activity rate; S1 = saline trial 1 activity rate; S4 = saline trial 4 activity; E1 = ethanol trial 1 activity rate; E4 = ethanol trial 4 activity rate; E1-S1 = difference in activity rates between ethanol trial 1 and saline trial 1; E4-S4 = difference in activity rates between ethanol trial 4 and saline trial 4; Tol/Sens = difference between E4-S4 and E1-S1