Skip to main content
. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Neuropharmacology. 2014 May 27;85:57–66. doi: 10.1016/j.neuropharm.2014.05.022

Figure 6. Comparison of modulator affinity and efficacy for different AMPA receptor mutations.

Figure 6

Efficacy and occupancy data from Table 2 for the effect of a given modulator on a given mutation in either flip (left) or flop (right) isoforms of GluA2 receptors has been normalized to the same modulator treatment for the respective wild type receptor isoform. Receptor occupancy is indicative of relative changes in modulator apparent affinity.