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Dose-dependent effect of 5-FU, LDH-5-FU, and BEZ-235 on HCT-116 cells.
Notes: A shows both 5-FU and LDH-5-FU produced cytotocitiy on HCT-116 cells at various concentrations. The effect of LDH-5-FU is much stronger than that of 5-FU alone. B shows BEZ-235 produced dose-dependent cytotoxic effect on HCT-116 cells in the concentration range from 25 nm to 400 nm. *** indicates P<0.001; n=3.
Abbreviations: LDH, layered double hydroxide; 5-FU, fluorouracil.
