Table 3.
Associations of decidual mRNA expression levels to different parameters of clinical severity and characteristics
| Clinical severity parameters and characteristics analysed a | Associated genes (all SPE samples) | Associated genes (smaller subset SPE samples) |
|---|---|---|
| Increasing systolic blood pressure (mmHg) | ERAP2↓ | NIL |
| Increasing diastolic blood pressure (mmHg) | NIL | NIL |
| Increasing proteinuria (dipstick +) | NIL | NIL |
| Decreasing level of platelets | NIL | NIL |
| Greater number of antihypertensive medications | ERAP2↓ | NIL |
| Required MgSO4 treatment | NIL | NIL |
| Earlier onset of SPE (weeks) | COL4A1↑ | COL4A2↑ |
| Earlier delivery of fetus (weeks) | LNPEP↑ | INHA↑, INHBB↑, COL4A2↑ |
| Decreasing infant weight percentile (%) | NIL | NIL |
| Decreasing placental weight (g) | NIL | NIL |
| Increasing maternal age (years) | NIL | NIL |
| Increasing gravidity | NIL | NIL |
| Increasing parity | COL4A2↑ | NIL |
a
Spearman's correlation for correlation of non-parametric data. ↑ denotes increasing expression of gene. ↓ denotes decreasing expression of gene.