Table 1.
Samples | No. of cells | Tumor formation | Histologic examination |
---|---|---|---|
miPS-LLCev | 1 x 102 | 0/4 | NA |
1 x 103 | 0/4 | NA | |
1 x 104 | 0/4 | NA | |
1 x 105 | 3/4 | malignant, angiogenesis | |
1 x 106 | 10/10* | malignant, angiogenesis, bleeding (2/10) | |
miPS-LLCevPT | 1 x 102 | 0/4 | NA |
1 x 103 | 0/4 | NA | |
1 x 104 | 0/4 | NA | |
1 x 105 | 5/5 | malignant, angiogenesis | |
1 x 106 | 5/5 | malignant, angiogenesis | |
miPS-LLCevDT | 1 x 102 | 0/4 | NA |
1 x 103 | 0/4 | NA | |
1 x 104 | 0/4 | NA | |
1 x 105 | 5/5 | malignant, angiogenesis | |
1 x 106 | 5/5 | malignant, angiogenesis |
PT: primary tumor cells; DT: disseminated tumor cells.
NA: not applicable.
*There are 2 in 10 mice were found to be bleeding with disseminated tumors in the mesentery.