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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Biomaterials. 2014 May 27;35(25):7194–7203. doi: 10.1016/j.biomaterials.2014.05.004

Figure 2.

Figure 2

The synthetic schemes of graft copolymer 5 and monomer III. Monomer I and Monomer II were firstly condensed into a linear alternating multiblock copolymer by NHS mediated amidation. After liberating the third amino group of monomer I, the side chains were gradually elongated on the main chain via a TMS controlled ROP of monomer III. To maximize the drug loading capacity, CPT was conjugated with glutamic acid and directly polymerized into the side chain, presenting a new method for drug loading.