Figure 2.

Characterization of the glucose-responsive nano-network. SEM images of nanoparticles (NPs) coated with chitosan and alginate (a) and formed nano-network (b). Inset is a gel-like nano-network adhered to the bottom of an inverted vial. (c) Laser scanning confocal microscopy image of the nano-network consisting of chitosan-coated NPs (encapsulated with FITC-stained insulin) and alginate-coated nanoparticles (encapsulated with rhodamine-stained insulin). (d) Viscosity and shear-thinning behaviors of the nano-network compared with pure nanoparticles. Inset shows that the collected nano-network is injectable with sufficient cohesiveness through a conventional syringe.