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Effects of calmodulin-dependent protein kinase II inhibitor KN-93 on cultured cortical neuron viability following treatment with 50 μM NMDA using the MTT assay.
I–VI: Sham, NMDA, 0.5 μM KN-93, NMDA + 0.25 μM KN-93, NMDA + 0.5 μM KN-93, NMDA + 1.0 μM KN-93 groups.
Data are expressed as mean ± SD, n = 6 for each group. aP < 0.01, vs. sham group; bP < 0.05, cP < 0.01, vs. NMDA group using one-way analysis of variance.
NMDA: N-methyl-D-aspartic acid.
